The independent predictors of in-hospital mortality included age (OR, 1.029; 95% CI, 1.013–1.045; p < 0.009), screened due to medical reason (OR, 1.799; 95% CI, 1.115–2.904; p = 0.016), SOFA (OR, 1.119; 95% CI, 1.042–1.202; p = 0.002), solid tumor (OR, 1.676; 95% CI, 1.065–2.638; p = 0.026), hematologic malignancy (OR, 3.166; 95% CI, 1.483–6.760; p = 0.003), total bilirubin (T-bilirubin; OR, 1.055; 95% CI, 1.006–1.106; p = 0.027), lactate level (OR, 1.166; 95% CI, 1.078–1.261; p < 0.001), and CRP level (OR, 1.027; 95% CI, 1.008–1.046; p = 0.005) after adjusting for confounders. This evidence concerns the gene CRP and hematologic disorder.