PLEKHG6 and colorectal cancer: However, gene set enrichment analysis of these findings suggested enriched expression of genes involved in immunological pathways relating to memory CD8 T cells and coexpression network analysis identified ACE expression in a cluster of coexpressed genes enriched for colorectal cancer risk susceptibility genes (e.g., LAMA5, PNKD, TOX2, PLEKHG6) [73].