ACE and type 2 diabetes mellitus: Genetically proxied ACE inhibition was associated with lower SBP (mm Hg per SD lower serum ACE concentration: −0.40, 95% CI −0.21 to −0.59, P = 4.2 × 10−5) and a lower risk of type 2 diabetes (odds ratio (OR) equivalent to 1 mm Hg lower SBP: 0.90, 95% CI 0.85 to 0.95, P = 1.3 × 10−4).