Considering that BMP6 expression was similarly induced by TLR4 stimulation in monocytes from HVs as well as in those from patients with SS, a critical step in the LAMP3/HSP70/BMP6 axis we identified is the expression of LAMP3 in the release of HSP70 via lysosomal exocytosis. This evidence concerns the gene BMP6 and synovial sarcoma.