Of note, CCR1 is an important receptor that is implicated in neutrophil trafficking to post-ischemic tissues (Reichel et al., 2006) and ischemia is an important co-morbidity associated with impaired healing in diabetic wound (Brem and Tomic-Canic, 2007; Armstrong et al., 1998). The gene discussed is CCR1; the disease is ischemia.