OFD1 and cystic kidney disease: On the same line, we demonstrated that modulation of autophagy improves the renal cystic phenotype (by reducing the number of renal cyst and improving the renal function) in Ofd1 mutant animals suggesting that the renal cystic disease in OFD type I is at least partially due to a non‐ciliary function of the OFD1 protein (Morleo et al., 2021).