Consistent with the previous finding that AKIP1 knockdown enhanced the expression of EMT-related marker E-cadherin in nonsmall-cell lung cancer cells [18], we again confirmed the elevated E-cadherin expression by AKIP1 knockdown in glioma, indicating the involvement of AKIP1 in regulating EMT process for the promotion of glioma. This evidence concerns the gene CDH1 and lung cancer.