Since amyloid polymorphism is generally considered to be closely related to the severity of symptoms of amyloidosis, and since physicochemical properties of polymorphs are sensitive to the chemical environment in which they are formed, integration of the structural and dynamical knowledge obtained by future systematic studies on various kinds of polymorphs would definitely advance our understanding of the molecular mechanism of various diseases not limited to lysozyme amyloidosis. This evidence concerns the gene LYZ and amyloidosis.