CASP3 and medulloblastoma: The knockdown of lncRNA CRNDE induces apoptosis via promoting the activity of caspase-3 in medulloblastoma cells (Song et al., 2016) Cleaved-caspase-3, caspase-9, and Bax elevation, and bcl-2 reduction are the results of HOTAIR downregulation in medulloblastoma cells (Zhao et al., 2020).