PRDX3 and medulloblastoma: Xu et al. (2014) found that over-expression of miR-22 stimulated apoptosis via inhibiting PAPST1 in medulloblastoma cell. MiR-378 was down-regulated in medulloblastoma. The over-expression of miR-378 showed promoting apoptosis through targeting UHRF1 in medulloblastoma (Zhang et al., 2017). MiR-383 negatively regulated PRDX3. The over expression of miR-383 and inhibiting PRDX3 could leads to stimulating apoptosis in medulloblastoma (Li et al., 2013).