There was a strong positive correlation between the in situ expression levels of PRL1, USP36 and Snail2 in these tissues (Figures 8A, –C), which was further corroborated by analyzing the total protein extracts of 26 freshly collected GBM tissue samples (Figures 8D, E and Supplementary Figure S7). This evidence concerns the gene PTP4A1 and glioblastoma.