Comparative study of the usefulness of a novel insulin therapy in
Japanese patients with Type 2 diabetes for concomitant use of an oral antidiabetic agent withtwice-daily dosing either of insulin aspart, biphasic insulin aspart-30, or insulin detemir:Two times Insulin injection Combined with oral therapy Efficacy Study (TWICEstudy). Here, INS is linked to type 2 diabetes mellitus.