Alb, TLC, TTR, RBP, and Tf have been used as nutritional prognostic factors for manyyears,17 and several studies have shown thatCRP has a significant positive correlation with poor prognosis.18 TTR has been used as a nutritional index for cachexia, because itcan reflect subtle changes in protein metabolism when evaluating the response to a change innutritional support, and for the diagnosis of irreversible cachexia when TTR does not improvefollowing administration of adequate nutritional therapy. This evidence concerns the gene TF and Cachexia.