NAFLD, non-alcoholic fatty liver disease; HCC, hepatocellular carcinoma; VLDL, very-low-density lipoprotein; PNPLA3, patatin-like phospholipase domain-containing protein 3; MBOAT7, membrane-bound O-acyl transferase 7; TM6SF2, transmembrane 6 superfamily member 2. Here, TM6SF2 is linked to hepatocellular carcinoma.