APOB and atherosclerosis: Elevated TG association with an increased risk of atherosclerotic cardiovascular disease (ASCVD) becomes insignificant after adjusting for non-HDL cholesterol (non-HDL-C), which represents the total concentration of all Apo B-containing lipoproteins [11]. The fibrate lowering of TG reduces the risk of cardiovascular events when measured per unit change of non-HDL-C [12,13].