The expression of P4HA2 increased in head and neck squamous cell carcinoma (HNSCC) (Kisoda et al., 2020), Oral Squamous Cell Carcinoma (OSCC) (Reis et al., 2020), cervical cancer (Cao et al., 2020b) and other cancers. Here, P4HA2 is linked to oral cavity squamous cell carcinoma.