The expression of P4HA2 increased in head and neck squamous cell carcinoma (HNSCC) (Kisoda et al., 2020), Oral Squamous Cell Carcinoma (OSCC) (Reis et al., 2020), cervical cancer (Cao et al., 2020b) and other cancers. This evidence concerns the gene P4HA2 and head and neck squamous cell carcinoma.