Among these genes, AZU1, CAMP, CCL5, CTSG, MMP9, MPO, PRTN3, RETN, RNASE2, and RNASE3 showed the highest node scores, suggesting that they may play causative roles in CML progression. The gene discussed is RNASE3; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.