Levels of ANKRD55 splice variants induced by AM580 in immature moDC compared to untreated cells were significantly higher in homozygous carriers of MS risk alleles but not significantly different in homozygotes of the protective alleles, though the scarcity of the latter genotype restricted the power of the test in this group (Supplementary Table S3). This evidence concerns the gene ANKRD55 and myeloid sarcoma.