AKT1 and neoplasm: Additionally, western blot showed that the MSJZD and cisplatin markedly abolished the expression of Vimentin, Snail, TGF-β1, p-AKT, p-GSK 3β in A549 tumor-bearing nude mice, but MSJZD had no effect on the total protein expression levels of AKT and GSK 3β (Figure 8C).