INS and diabetic kidney disease: At the 17th week, the blood insulin level of the DKD group was significantly lower than that of the control group (p = 0.020), but the insulin levels of Chaga50 and Chaga100 increased significantly compared with the DKD model (Both: p < 0.05), while there was no significant difference between the normal group and the Chaga100 group (p = ns).