NR2F1 and neoplasm: To this end, we took lung tissues from the SM model, stained them for NR2F1 and MenaINV expression (Supplementary Fig. 7a), and quantified the percent of single and double-positive tumor cells in single DTCs and in small (≤10 tumor cells), medium (11–300 tumor cells), and large (≥300 tumor cells) micro-metastases (Supplementary Fig. 7b).