Therefore, our aims were to (1) compare the different N biomarkers CSF t-tau, medial temporal atrophy (MTA) visual rating on MRI, hippocampal volume (HV), serum neurofilament light (NfL), and serum glial fibrillary acidic protein (GFAP) to each other and to markers of A and T and (2) determine their predictive value for clinical progression and cognitive decline beyond A and T in a sample of cognitively normal individuals with subjective cognitive decline (SCD). Here, GFAP is linked to Mental deterioration.