Nine genes (STC1, ANKZF1, STC2, SDHB, SUCLG2P2, P4HA1, PPFIA4, GPC1 and PCK1) in COAD and 4 genes (TSTA3, IDH3A, PKP2 and ACO2) in READ were found to be significantly associated with overall survival (OS) (p value < 0.05) (Table 3). The gene discussed is PPFIA4; the disease is colon adenocarcinoma.