LYVE1 and melanoma: However, the percentages of Lyve1+ or CD32b+ intratumoral vessels were significantly higher in HCmel12 in comparison to the other melanoma metastases (Lyve1+: 59.9% ± 6.3; CD32b+: 9.2% ± 3.4) indicating a mixed sinusoidal and capillarized molecular phenotype in a minor fraction of HCmel12 vessels (Fig. 4D, E).