Similarly, the differentially expressed patterns between patients with T2D and CAD – both chronic and acute- in comparison with healthy diabetics showed an effect on Cardiovascular System Development and Function, Cellular Development, Cellular Function, and Maintenance with a score of 17 and 6 focus molecules (EG-VEGF, LAP (TGF-b1), Leptin, PD-ECGF, Serpin F1, and TIMP-4), in addition to functions associated with Cell-To-Cell Signaling and Interaction, Cellular Compromise, Inflammatory Response, with a score of 2 and 1 focus molecule (DPP-IV) (Fig. 6G). The gene discussed is TIMP4; the disease is coronary artery disorder.