PLAU and cancer: Further, they analyzed 84 cancer associated genes and showed nuclear factor κB (NF-κB), platelet derived growth factor (PDGF), matrix metallopeptidase 9 (MMP-9), urokinase plasminogen activator (uPA), melanoma cell adhesion molecule (MCAM), metastasis associated 1 family, member 2 (MTA2) to be significantly altered after AN-152 treatment [10].