The use of agonist GnRH is more physiologic but has a luteolytic effect, reducing the half-life of the corpus luteum, requiring more robust luteal phase support to lower implantation rates, and causing a higher risk of miscarriage in cycles transferred to fresh.14In our study, we did not observe a difference in the number of abortions when we compare the three groups. Here, GNRH1 is linked to spontaneous abortion.