STING1 and schistosomiasis: In contrast to the requirement of STING for the formation of egg granulomas in liver of mice infected with S. japonicum, Sting-/- mice showed no change in granuloma numbers and area when compared to WT animals in response to S. mansoni infection, which might reflect the difference in the pathogenesis of schistosomiasis caused by S. japonicum and S. mansoni [3,39].