ALK and neoplasm: A total number of 493 analyses (MPS, EGFR PCR, ALK IHC and/or FISH, ROS1 IHC and/or FISH, PD-L1 IHC) of predictive biomarkers were performed on air-dried smears, cellblocks, and biopsy tissue in the study group (all procedures included: EBUS cytology, bronchial brushes and forceps biopsies from bronchoscopy, transthoracic tumor biopsy or tissue from previous or later operation).