CCL18 and acrodermatitis enteropathica: To study the chemokine (MCP-1, MCP-3, MCP-4, PARC, and TARC) and cytokine (IL-10, IFN-γ) production induced by E. multilocularis antigen (EmAg), PBMCs from AE patients were stimulated and the release of cytokines and chemokines into cell culture supernatants was quantified by specific ELISA (Fig 2).