Hepatic steatosis index (HSI), NAFLDfibrosis score (NAFLDS), alanine aminotransferase (ALT)/AST, and fibrosis-4(FIB-4) were not able to correctly predict severe steatosis on liver biopsy.APRI showed high specificity of 82% and low sensitivity of 54%. This evidence concerns the gene GPT and Hepatic steatosis.