Neither mutants or wild-type littermates had otitis externa at weaning age or as older adults [MecomJbo/+ (P22, n=14; P84, n=12 ears); Mecom+/+ (P22, n=14 ears); Fbxo11Jf/+ (P21, n=13; P57-P223, n=41 ears); Fbxo11+/+ mice (P21, n=10 ears)]. Here, FBXO11 is linked to otitis externa.