It follows that if the viral load is low, the effects of SARS‐CoV‐2 infection will minimal, but in those situations in which Ang II production is tonically activated, for example, obesity, hypertension, and diabetes mellitus, where it is likely that ACE2 receptor density is increased, SARS‐CoV‐2 will infect tissues more avidly, the Ang II‐AT1R pathway will be activated more intensely, and the inflammatory response will be more severe. Here, AGT is linked to obesity due to melanocortin 4 receptor deficiency.