AKT1 and acute myeloid leukemia: In this work, we described that ASK triggered both cell autophagy and apoptosis in the acute myelogenous leukaemia FAB‐M2 cell line HL‐60 through the key LKB1‐AMPK and PI3K/Akt‐regulated mTOR signalling pathways, which could better understand the relationship between autophagy and apoptosis during ASK‐induced cell death.