RIPK1 and Alzheimer disease: Multiple lines of evidence have shown that RIPK1 is involved in modulating numerous signalling pathways in neuronal cells such as apoptosis, autophagy and necroptosis.18, 19, 20, 21, 22, 23, 24 Apoptosis has been studied intensively in AD, but the outcomes remained contradictory.25, 26, 27, 28, 29, 30, 31, 32, 33 In this study, increased caspase‐3 activity was observed in cells treated with Aβ, whilst the activities of caspase‐8 and caspase‐9 were unchanged.