As expected, the protein expression of RIPK1, p‐RIPK1, RIPK3, p‐RIPK3, MLKL and p‐MLKL showed a similar expression trend in cells treated with Aβ (Figure 4B), suggesting that Aβ and APP are capable of activating necroptotic‐cell death in AD. The gene discussed is RIPK1; the disease is Alzheimer disease.