We perform an epigenome-wide DNAme analysis in cervical smear samples from women who were subsequently diagnosed with ovarian cancer, and in matched controls (i.e. the Discovery Set), and establish/validate the WID-OC-index (Women’s risk IDentification for Ovarian Cancer index) which we then further validate in an independent set of cervical samples (i.e. External Validation Set). Here, BGLAP is linked to ovarian carcinoma.