The 16 robust associations from the anthropometrics category pertained to BMI (including childhood BMI and early life body size) and waist-to-hip ratio (WHR) with decreased risk of total breast cancer [164, 250, 255, 299], estrogen receptor positive (ER+) [250, 299], and negative (ER−) disease [164, 250, 299]); BMI with increased risk of kidney/renal cell [240] and endometrial [293] cancer, and adult height with increased overall [204] and ovarian cancer risk [194]. The gene discussed is ESR1; the disease is cancer.