Genes SLC22A4, OTUD3, PARK7, NOTCH4, GPR35, DAP, UBA7, MST1, MST1R, CD40, TAP2, NICNI, RGS14, LINCO1475, GBAP1, NUCKS1, HCG23, CCDC88B, HEART3, and ERAP2, have been previously associated with IBD, CD or UC. This evidence concerns the gene NOTCH4 and inflammatory bowel disease.