The effects of BMI, WHR, and WHRadjBMI on endometriosis, PCOS, pre-eclampsia, and UF were attenuated (95% CIs of ORs all contain 1) when adjusted for leptin, fasting insulin, or insulin sensitivity as measured by the modified Stumvoll Insulin Sensitivity Index (ISI) (Fig 4B, S16 Table). Here, INS is linked to endometriosis.