LEP and polycystic ovary syndrome: The effects of BMI, WHR, and WHRadjBMI on endometriosis, PCOS, pre-eclampsia, and UF were attenuated (95% CIs of ORs all contain 1) when adjusted for leptin, fasting insulin, or insulin sensitivity as measured by the modified Stumvoll Insulin Sensitivity Index (ISI) (Fig 4B, S16 Table).