Examples of cytokine-receptor pairs implicated in MSC tumour tropism are SDF-1 & C-X-C motif chemokine receptor-4 (CXCR4), VEGF & VEGFR, MCP-1 & C-C motif chemokine receptor (CCR2), epidermal growth factor (EGF) & EGFR, and hepatocyte growth factor (HGF) & c-Met [51]. The gene discussed is EGFR; the disease is neoplasm.