MAPT and Alzheimer disease: The two AD participants (#1 and #2) showed a typical AD-like pattern on Tau PET, including high retention across frontal, parietal, and temporal cortices and the medial temporal lobe; e.g. SUVR ≥ 1.5 (average of left and right) across composite ROIs corresponding to Braak stages I-V (see Fig. 1 and [Supplementary] Table S1).