In this sense, Cheon et al.12 designed spherical 15 nm zinc-doped iron oxide NPs (Zn0.4Fe2.6O4) with an exceptionally high Ms value (161 Am2kgFe−1) coated with a targeting antibody for death receptor 4 (DR4) in colon cancer cells. This evidence concerns the gene TNFRSF10A and malignant colon neoplasm.