KEGG analysis indicated that upregulated genes in MIN6 cells under proinflammatory cytokine stimulation were primarily involved in the “Herpes simplex virus infection,” “antigen processing and presentation,” “TNF signaling pathway,” and “type 1 diabetes,” whereas downregulated genes were related to “cell cycle,” “necroptosis,” and “Rap1 signaling pathway”. Here, TNF is linked to type 1 diabetes mellitus.