the expression level of GAS5 in cancer tissues was lower than that in normal tissues adjacent to cancer (p < 0.05, Figure 1(a)), and the expression level of GAS5 in CRC cell lines SW480 and HCT116 was significantly downregulated compared with that in normal colon epithelial cells NCM460 (p < 0.01, Figure 1(b)). Here, GAS5 is linked to colorectal carcinoma.