PICSAR and male infertility: In the cytoplasm, NLC1-C is the target of miR-320a and miR-383; while accumulated in the nucleus of spermatogonia and primary spermatocytes, it is suggested to repress the expression of miR-320a and miR-383 by direct binding to nucleolin, resulting in the hyperactive proliferation of germ cells, which leads to male infertility [71].