PNPLA3 and fatty liver disease: In the LBC, the PSD3 rs71519934 minor allele (186T) was associated with lower prevalence of liver steatosis (P = 5.9 × 10−6), fibrosis (P = 0.006), inflammation (P = 9.9 × 10−7) and ballooning (P = 0.002) (Table 2) using binary logistic regression analysis under an additive genetic model adjusted for age, gender, body mass index (BMI), centre of recruitment and the PNPLA3 rs738409.