HSPA5 and acute myeloid leukemia: To demonstrate that GRP78 is overexpressed in AML blasts by gene expression analysis, we utilized samples from three publicly available databases (RNAseq from TARGET24(pediatric): N = 159; microarray data from TCGA25 (adult): N = 244 and MILE study26 (adult and pediatric): N = 252, downloaded from Bloodspot27 (Fig. 1a, b and Supplementary Fig. 1) in comparison to cord blood (CB) for RNAseq or HPC from adult bone marrow28 for microarray.