HSPA5 and acute myeloid leukemia: We further demonstrated that GRP78 is highly expressed on the cell surface of >50% of 14 primary AML samples screened (de novo: N = 6, relapsed: N = 4, therapy-related: N = 4) (Fig. 1d, Supplementary Table. 1), and in all 5 AML PDX samples (Fig. 1e).