A study of 12 LRRK2-GBA dual mutation carriers (all with LRRK2 G2019S; 9 with GBA N370S, 2 with E326K and 1 with R496H) among 556 PD patients reports no significant differences in clinical motor scores, motor fluctuations, freezing of gait, and number of patients reaching Hoehn & Yahr stage 3 compared with carriers of single-mutation or non-carriers [93]. The gene discussed is LRRK2; the disease is Parkinson disease.