A genome sequence analysis of E. coli strain 536 revealed that the pks island was fully conserved in this strain, but we detected, in comparison to the published colibactin-producing newborn meningitis isolate IHE3034 as well as to K-12 laboratory strain MG1655, a 6.1-kb chromosomal deletion between uvrC and fliY (see Fig. S1 in the supplemental material), which also includes the uvrY gene encoding the response regulator UvrY of the BarA-UvrY two-component regulatory system (TCS) (49). This evidence concerns the gene LIN9 and meningitis.