This SNP was previously associated with host response to experimental infection of nursery pigs with PRRSV (Boddicker et al. 2012) and is in high LD with the putative causative mutation for this effect in the GBP5 gene (Koltes et al. 2015), which plays a role in immune regulation and in mediating inflammatory immune response in the mouse (Shenoy et al. 2012). The gene discussed is GBP5; the disease is infection.