Since methylation of STING and cGAS promoters has been implicated in the loss of STING or cGAS protein expression, we analyzed TCGA NSCLC methylation data and sought to restore STING or cGAS expression in cell lines using the demethylating agent 5ʹAZADC (Figure 6). The gene discussed is STING1; the disease is non-small cell lung carcinoma.