TGFB1 and endometriosis: We also have shown that, in a mouse model of endometriosis, treatment with TMP significantly reduced lesion weight and the extent of lesional fibrosis and alleviated hyperalgesia, mostly likely through the reduction of lesional aggregation of platelets and the lesional expression of TGF-β1, NK1R, α-SMA, and collagen I. Our findings indicate that TMP can be an excellent drug candidate for treating endometriosis.